tnf-α , human — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19584L	TNF-α (31-45), human acetate	TNF-α (31-45), human acetate(144796-71-4 free base)	Others
	TNF-α (31-45), human acetate is a peptide of tumor necrosis factor-α.		Others
TP1626	TNF-α (46-65), human
	Human TNF alpha (46-65) peptide.
T19584	TNF-α (31-45), human		Others
	TNF-α (31-45), human is a peptide of tumor necrosis factor-α.		Others
TP1537	TNF-α (10-36), human
	TNF-α (10-36), human is a potent pro-inflammatory cytokine involved in the acute phase stress response.
TP1479	TNF-α (10-36), human (TFA) (144796-70-3 free base)	TNF-α (10-36), human (TFA)
	TNF-α (10-36), human (TFA) is a peptide of human TNF-α.
TP1636	TNF-α (31-45), human TFA (144796-71-4 free base)	TNF-α (31-45), human TFA
	TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α.
TP1669	TNF-α (46-65), human TFA (144796-72-5 free base)	TNF-α (46-65), human TFA
	TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T76026	TNF-α (31-45), human TFA
	TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α. Tumour necrosis factor alpha (TNF alpha) is an inflammatory cytokine that induces necrosis or apoptosis [1] .
T10866	Cot inhibitor-2		TNF , MAPK
	Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.		TNF , MAPK
T9901	Adalimumab		TNF
	Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.		TNF
T10865L	Cot inhibitor-1 hydrochloride	Cot inhibitor-1 hydrochloride(915365-57-0 Free base)	TNF , MAPK
	Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-α in human whole blood (IC50 = 5.7 nM).		TNF , MAPK
TN1520	Isoforskolin	Coleonol B	IL Receptor , TNF
	Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.		IL Receptor , TNF
T2367	SKF-86002	SKF86002	p38 MAPK , TNF
	SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).		p38 MAPK , TNF
T5754	Kavain		NF-κB , GABA Receptor
	Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.		NF-κB , GABA Receptor
T2384	Pomalidomide	CC-4047	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Pomalidomide (CC-4047) inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
TN6694	5,6-Benzoflavone	β-Naphthoflavone,beta-NF	Antioxidant
	5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...		Antioxidant
T11699	J-113863		CCR
	J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...		CCR
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T14381	AZD7624	AZD-7624	p38 MAPK , TNF
	AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.		p38 MAPK , TNF
T70562	PD 144795
	PD 144795 inhibited neutrophil adhesion to tumour necrosis factor-α (TNF-α)-activated human umbilical vein endothelial cells